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Tuesday 25 November 2014
Dr. Margaret Foti, PhD, MD (hc)
Reflections on the Global Cancer Research Landscape

Tuesday 23 September 2014
Prof. Charles Swanton
Cancer Evolution: Causes and Consequences

Thursday 11 September 2014
Dr. Matt Roberts
Interrogating protein dynamics within living cells using protein-based reporters derived from NanoLuc Luciferase

Thursday 10 July 2014
Prof. Alain Thierry
Multimarker analysis of circulating cell-free DNA toward personalized medicine for colorectal cancer

Thursday 12 June 2014
Prof. Alexander Eggermont
Spectacular Advances in Drug Development: Melanoma as Model System for both Targeted and Immunotherapeutic Approaches

Wednesday 28 May 2014
Dr. Andreas Buness
Background & Perspectives in Bioinformatics

Wednesday 30 April 2014
Prof. Carlos Caldas
Molecular stratification and molecular monitoring in breast cancer

Tuesday 1 April 2014
Lisa Ryden Lund University, Clinical Sciences, Department of Surgery
Diagnosis of tumor progression in the clinical setting

Monday 31 March 2014
Dr. Luca Agnelli
Improved risk stratification in myeloma using a microRNA-based classifier

Wednesday 19 March 2014
Dr. Giovanni Crisafulli
Applying Bioinformatics to Clinical Research

Monday 10 March 2014
Dr. Patrick Meraldi, Dr.Stephen Royle, Dr. Marina Mapelli
Cell Division - 2014 Lectures Ph.D. Programme in Complex Systems in Medicine and Life Sciences - University of Torino

Tuesday 4 March 2014
Pere Roca-Cusachs, Albrecht Schwab, Christoph Ballestrem, Kristian Franze
Workshop on "Mechanisms of Cell Mechanosensing"

Friday 28 February 2014
Prof. Julian Downward
Mechanisms of transformation by RAS oncogenes: searching for novel therapeutic approaches

Thursday 27 February 2014
Prof. Paola Chiarugi
Reciprocal metabolic deregulation of tumors and their stroma: a new druggable synergy

Thursday 20 February 2014
Dr. Alessandro Guffanti
Terra Incognita: biology-oriented explorations of Next Generation Sequencing experimental results

Friday 7 February 2014
Dr. Giovanni Germano
Role of Macrophage targeting in the anti-tumor activity of Trabectedin

Thursday 14 November 2013
Ivana Bozic
Dynamics of Targeted Cancer Therapy

Thursday 17 October 2013
Yardena Samuels
Mutational and Functional analysis of melanoma-filling in the gap

Monday 14 October 2013
Silvia Perego - Promega Milano
Advances in Cell-Based Assays: Get More Biologically Relevant Data

Wednesday 24 July 2013
Caroline Dive
Circulating Tumour Cells,as Biomarkers and for Exploring Biology

Friday 28 June 2013
AlphaTechnology: a new approach to cell based and biochemical assay

Tuesday 25 June 2013
Tim Maughan
Molecular selection of therapy in advanced colorectal cancer - building the platforms in clinic and laboratory

Wednesday 19 June 2013
Pete Smith
Challenges in translating the cancer genome into impactful drugs

Friday 7 June 2013
Unraveling Cancer One Base at a Time - How Next Generation Sequencing can uncover cancer genetics

Friday 24 May 2013
Dr. Maria Comanescu and Prof. Giovanni Bussolati
Triple negative breast cancers

Monday 22 April 2013
Prof. Massimiliano Mazzone
Macrophages in tumor hypoxia:should they stay or should they go?

Thursday 4 April 2013
Dr. Ion Cristian Cirstea
RAS GTPases germline mutations lead to dysregulated signaling and developmental disorders

Monday 18 March 2013
Patrick Caswell
Integrins and endocytic trafficking in the regulation of intracellular signalling

Friday 15 March 2013
Dr. Michele Milella
Beyond single pathway inhibition: MEK inhibition-based vertical and lateral combination strategies to achieve synergistic anti-tumor activity

Wednesday 6 March 2013
Lukas A. Huber, Giorgio Scita
Endosomal signaling

Tuesday 5 March 2013
Sharon Tooze, Francesco Cecconi, Marco Sandri, Francesca Fanelli
Autophagy and Computational Structural Biology

Friday 8 February 2013
Yvonne Jones
The structural biology of cell guidance and adhesion

Friday 1 February 2013
Patrick Mehlen
"The dependence receptor notion: from a cell biology paradigm to alternative targeted cancer therapies"

Friday 16 November 2012
Prof. Robert Bast

Thursday 15 November 2012
Prof. Antonello Spinelli
"Cerenkov light, a new preclinical approach to look at tumours in vivo... and more"

Monday 12 November 2012
Prof. Mario Nicodemi
"Stochastic dynamics of stem cell reprogramming"

Friday 26 October 2012
Annarosa Leri
Cardiac Stem Cells and Myocardial Regeneration

Friday 12 October 2012
Prof. Michael Simons
"VEGF receptor trafficking and signaling."

Thursday 26 July 2012
Prof. David Sidransky
Markers and Models to personalize cancer therapy

Friday 29 June 2012
Prof. Glauco Souza
"Levitating Cells for Developing In vivo-lIke 3D Cell Culturing Tools and Assays."

Friday 25 May 2012
Prof. Dr. Amparo Acker-Palmer
"Mechanisms of tumor invasion and evasive resistance to anti-angiogenesis therapy"

Friday 18 May 2012
Prof. Stefan Offermanns
"Novel roles of B-plexins and GPCRs in tumour cell metastasis"

Monday 7 May 2012
Dr. Riccardo Dalla Favera
"The Genome of Diffuse Large B-Cell Lymphoma"

Friday 20 April 2012
Prof. Michael Clague
Receptor trafficking and signaling: governance by ubiquitin and phosphorylation.

Friday 13 April 2012
Dr. Manuel Hidalgo
Pancreatic Cancer: From Molecular Understanding to Personalized Treatment

Friday 24 February 2012
Prof. Hellmut Augustin
"Control of angiogenesis and vascular homeostasis through the angiopoietin/Tie system.

Friday 10 February 2012
Prof. Fortunato Ciardiello
"Molecular targeted therapies in metastatic colorectal cancer"

Thursday 9 February 2012
Prof. Andrea Ventura
"Oncomir-1 in cancer and development: a tale of mice and men"

Friday 3 February 2012
Dr. Laura Soucek PhD
"Pre-clinical validation of Myc as a target in cancer therapy"

Wednesday 23 November 2011
Josep Tabernero
"The introductionof biomarkers in early drug development"

Tuesday 22 November 2011
Yosef Yarden
EGFR and HER2 in cancer: molecular mechanisms and targets for therapy

Friday 23 September 2011
"Improving preclinical models for molecular targeted (and non-targeted) adjuvant or metastatic therapies: antiangiogenic drugs as a paradigm"

Friday 2 September 2011
Maurizio Scaltriti PhD
Understanding and overcoming anti-HER2 resistance

Friday 20 May 2011
Prof. Julian Downward
RAS and PI 3-kinase signaling networks in cancer

Thursday 19 May 2011
Roberto Girelli
Radiofrequency ablation of stage III pancreatic cancer: a wind of change ?

Friday 6 May 2011
Jun Takagi
Structure of plexin/semaphorin ectodomain complex reveals a possible signal transduction mechanism

Thursday 21 April 2011
Tiziana Crepaldi
Emerging roles of HGF/Met in cardiac function

Friday 25 March 2011
Miguel Angel del Pozo
Biomechanical remodeling of the microenvironment by stromal Caveolin-1 favors tumor progression

Monday 28 February 2011
Dr. Guido Serini
Regulation of endothelial cell adhesion by integrin conformation and traffic: implications for tumor angiogenesis

Monday 28 February 2011
Dr. Sara Zanivan
Quantitative MS-based proteomics in angiogenesis

Monday 28 February 2011
Dr. Katie Bentley
Symbiosis of simulation and experimentation: discovering novel mechanisms in angiogenesis

Monday 28 February 2011
Dr. Andras Cziro
Vasculogenesis and collective movement of endothelial cells

Friday 25 February 2011
Silvio Gutkind
Novel Insights into Pro-Angiogenic and Anti-Angiogenic Signaling Circuitries in Cancer

Friday 18 February 2011
Hugo Marsiglia
Breast Cancer: Meta-analysis 2010 and Partial Breast Irradiation as Model of Clinical and Translational Research

Wednesday 16 February 2011
Dario Fortunati
Tissue Transglutaminase, a polyhedric enzyme: friend or foe?

Friday 11 February 2011
Prof. Giannino Del Sal
Regulation and dysregulation of the p53 network

Thursday 10 February 2011
Dr. Matthew Smalley
Stem cells, cancer stem cells and breast cancer heterogeneity

Thursday 3 February 2011
Patrick Mehlen
The dependence receptor notion: from a cell biology paradigm to an anti-cancer strategy

Friday 26 November 2010
Reinhard Faessler
Genetic analysis of integrin signalling in mice

Friday 19 November 2010
Thierry Galli
Membrane trafficking in neuronal & epithelial morphogenesis

Monday 25 October 2010
Massimiliano Mazzone
PHD2 oxygen sensor: a gateway system for angiogenesis and arteriogenesis

Friday 15 October 2010
Oriol Casanovas
An update on tumor malignization after anti-angiogenic therapies

Friday 24 September 2010
Giovanni Melillo
Targeting Hypoxia Inducible Factor 1 (HIF-1) for cancer therapy

Monday 12 July 2010
Prof. Luciano Di Croce
Epigenetic mechanisms of mammalian gene regulation in normal and cancerous cells

Tuesday 6 July 2010
Marino Zerial
Systems Analysis of Endocytosis and Signalling

Wednesday 16 June 2010
Antonio Celani
Bacterial strategies for chemotaxis response

Wednesday 16 June 2010
Alberto Puliafito
Collective and single cell behavior in epithelial contact inhibition

Monday 14 June 2010
William Kaelin
The von Hippel-Lindau Tumor Suppressor Protein: Insights into Cancer and Oxygen Sensing

Tuesday 8 June 2010
Thomas Vaccari
Endocytosis, Signaling and Tumor Suppression: Vacuolar-ATPase Controls Notch Trafficking And Activation in Drosophila

Friday 4 June 2010
Lena Claesson-Welsh
In vivo signal transduction regulating VEGF-induced vascular permeability

Friday 7 May 2010
Marco Masseroli
Integration, Mining and Search of Genomic and Proteomic Information

Friday 7 May 2010
Aldo Scarpa
Molecular Features of Pancreatic Endocrine Tumours

Friday 23 April 2010
Alda Tufro
Role of Sema3a in kidney development and disease

Friday 9 April 2010
Francesca Ciccarelli
"Evolutionary Genomics of Cancer"

Thursday 8 April 2010
Martina Santambrogio
Role of the retromer complex in Arabidopsis thaliana development

Monday 29 March 2010
Ajit Muley
FRP4: Novel candidate in anti-angiogenesis

Monday 1 March 2010
Robert Insall
A pseudopod-centred view of eukaryotic chemotaxis, and numerical models to test it

Monday 1 March 2010
Keith Mostov
Formation of multicellular epithelial structures

Monday 1 March 2010
Holger Gerhardt
Mechanisms of vascular patterning a tale of leaders and followers

Monday 1 March 2010
Andrea Parmeggiani
Motors, filaments and cytoskeletal transport

Friday 26 February 2010
Johanna Ivaska
Novel regulators of integrin function and traffic in cancer

Monday 22 February 2010
Enrico Bucci
Biological data mining by bibliometric measurements

Monday 25 January 2010
Francesco Retta
Structural characteristics and functional behaviour of KRIT1: a framework for understanding Cerebral Cavernous Malformation pathogenesis

Tuesday 19 January 2010
Claudio Schneider
Stromal microenviroment: its precursor cells and their role in serous ovarian carcinoma

Monday 18 January 2010
Mario Nicodemi
Symmetry breaking at X chromosome inactivation

Thursday 3 December 2009
Dr. Gamba - Dr. Corà
Presentazione dell'unità di Systems Biology

Friday 27 November 2009
Sophie Chauvet
Semaphorin 3E/Plexin D1 signaling in development and cancer

Friday 20 November 2009
G. Paolo Dotto
Tumor suppressing function of Notch and Notch-interacting pathways

Thursday 19 November 2009
Maria Antonietta Vanoni
Towards the understanding of the role of novel flavoproteins in health and disease: an enzymologist's look at Seladin-1/DHCR24 and MICAL

Friday 13 November 2009
John Laterra
Primary Brain Malignancies: Oncogenic Mechanisms and Emerging Therapeutics

Wednesday 11 November 2009
Gaetano Finocchiaro
Glioblastoma multiforme: update on the genetics and novel treatments

Friday 30 October 2009
Fabrizio d'Adda di Fagagna
Molecular mechanisms of cellular senescence in ageing and cancer

Friday 16 October 2009
Luca Scorrano
Keeping mitochondria and endoplasmic reticulum in shape: a matter of cell life, differentiation and death

Friday 2 October 2009
Jim Norman
Integrin trafficking and cell migration

Friday 25 September 2009
Peter Friedl
Collective cancer invasion, interaction with the microenvironment and resistance to therapy

Friday 24 July 2009
Victor Velculescu
Integrated genomic analysis of human cancer

Friday 10 July 2009
Jan Hoeijmakers
DNA damage: impact on cancer, aging and longevity

Friday 26 June 2009
David Tulasne
"Regulation of the Met receptor by proteolytic cleavages"

Friday 12 June 2009
Gerhard Christofori
Molecular dissection of EMT and tumor invasion

Friday 22 May 2009
Nicholas Denko
Manipulating hypoxic tumor metabolism for therapeutic gain

Wednesday 20 May 2009
Maria Dafne Cardamone
The dual roles of ERalpha as ligand-independent activator and ligand dependent repressor of EMT in breast cancer cells

Monday 27 April 2009
Teijo Pellinen
Genome-scale RNAi analysis of integrin β1 activation in prostate cancer cells using a novel cell spot microarray method

Friday 24 April 2009
Gera Neufeld
Class-3 semaphorins as inhibitors of tumor progression: Similarities, differences and puzzles

Friday 3 April 2009
Joelle Roche
Semaphorin SEMA3F, a tumor suppressor gene in lung cancer

Wednesday 25 March 2009
Paola Chiarugi
Epigenetic and environmental cues in plasticity of cell motility during metastatic dissemination

Monday 9 March 2009
Sabine Tejpar
Molecular determinants of sensitivity to EGFR inhibition in colorectal cancer

Friday 6 March 2009
Mario Nicodemi
Gene regulation and higher order nuclear organization

Friday 6 March 2009
Massimo Vergassola
Strategies of chemotaxis in bacteria and eukaryotes

Thursday 5 March 2009
Chris Janetopoulos
Mechanisms of cell polarization in D. Discoideum

Thursday 5 March 2009
Roland Wedlich-S�ldner
Mechanisms of cell polarization in yeast

Friday 27 February 2009
Jakub Swiercz
Molecular dissection of plexin-B1-mediated RhoA signalling

Wednesday 25 February 2009
Beatrice Bodega
Dissecting the higher order chromatin structure of the 4q35.2 locus at the basis of facio-scapulohumeral distrophy

Friday 20 February 2009
Akira Orimo
Evolution to tumor-promoting stromal myofibroblasts

Friday 6 February 2009
Amedeo Columbano
Triiodothyronine, a multi-organ mitogen with antitumoral and antisteatogenic effects

Tuesday 27 January 2009
Salvatore Oliviero
MYC-dependent chromatin phosphorylation induces cell transformation

Monday 26 January 2009
Riccardo Fodde
Cancer Stem Cells: are you a Juventus or Torino supporter?

Tuesday 20 January 2009
Akira Orimo

Thursday 18 December 2008
Antonia Follenzi
Reconstitution of the liver with LSEC (liver sinusoidal endothelial cells) for biological studies and cell and gene therapy applications

Friday 12 December 2008
Andrea Graziani
Dicylglcyerol kinase alpha mediates Src-sustained pro-migratory and invasive signaling

Wednesday 26 November 2008
Giampaolo Tortora
Mechanisms of resistance to anti-EGFR drugs and development novel therapeutic strategies

Thursday 6 November 2008
Christos Sotiriou
Taking gene expression profiling to the clinic: when will molecular signatures become relevant to patient care?

Tuesday 28 October 2008
Giorgio Stassi
Colorectal cancer stem cells as targets of anti-tumor therapy

Monday 27 October 2008
Dr. Giovanni Cenci
Telomere capping and cellular checkpoints: clues from fruit flies

Friday 10 October 2008
Giorgio Inghirami_yep
Why should we care about the Anaplastic Lymphoma Kinase?

Monday 6 October 2008
Leight Zawel
Development of IAP Antagonists as anti-cancer therapeutics

Wednesday 1 October 2008
Ben Ho Park
Identification, validation and Development of mutant PIK3CA Targeted Therapies

Tuesday 30 September 2008
Marta Irigoyen
Lymphatic endothelial cells response to hypoxia. Influence on lymphatic endothelial cells and NSCLC adhesion

Tuesday 15 July 2008
Cristina Lo Celso
Seeing is believing. Live animal tracking of hematopoietic stem cells in their niche(s)

Tuesday 1 July 2008
Mario Secchi
How to detect clinical and local severity in acute pancreatitis. The role of HGF.

Friday 16 May 2008
Christopher Heeschen
Metastatic cancer stem cells: a new target for anti-cancer therapy?

Wednesday 16 April 2008
Achim Krùger
Co-operation of uPA and TIMP-1 in the Creation of a Pro-Metastatic Niche via Hepatocyte Growth Factor-Signaling in the Liver

Wednesday 19 March 2008
Tobias Sjblom, PhD
Genome-wide mutational analyses of breast and colorectal cancers

Monday 10 March 2008
Thorarin Blondal and Thorunn Rafnar
Common Genetic Variation as a Cause of Cancer Predisposition

Thursday 6 March 2008
Erica Lantelme
Receptor revision in peripheral T cells from normal donors and from patients with chromosomal instability syndromes"

Tuesday 26 February 2008
Luigi Dogliotti and Alfredo Berruti
"Neuroendocrine aspects of prostate cancer: basic research and clinical importance"

Friday 15 February 2008
Silvia Marsoni
"Target to treatment: the lesson learned from the clinical development of TKIs"

Wednesday 6 February 2008
Curzio Ruegg
"Irradiated stroma selects for metastatic tumor escape variants though inhibited angiogenesis"

Monday 28 January 2008
Guus van Dongen
"Immuno-PET: A navigator in monoclonal antibody development and applications"

Friday 25 January 2008
Piero Borasio
"Possibilità e limiti della chirurgia nel trattamento dei tumori primitivi e secondari del polmone e della pleura"
S.C. a D.U. Chirurgia Toracica ASO San Luigi Gonzaga Orbassano (To)

Giuseppe Giaccone
"Lung Cancer Beyond Surgery"
Medical Oncology Branch CCR, National Cancer Institute Bethesda, USA

Tuesday 8 January 2008
Daniel Louvard
"Notch and Wnt signal integration in the mouse intestine"


The Candiolo Cancer Institute is a private non-profit institution founded and supported by the Fondazione Piemontese per la Ricerca sul Cancro-Onlus (FPRC) and operated by the Fondazione del Piemonte per l’Oncologia (FPO: co-founded by FPRC and the Regione Piemonte).